| 11beta-hydroxysteroid-dehydrogenase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| anti ADD | | | DUKE |
| anti aflatoxin | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti aggregant | | | DUKE |
| anti aging | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti allergic | 50857 | A drug used to treat allergic reactions. | DUKE |
| anti angiogenic | 48422 | An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. | DUKE |
| anti arrhythmic | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| anti bacterial | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti cancer | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti complementary | | | DUKE |
| anti dermatitic | 50177 | A drug used to treat or prevent skin disorders or for the routine care of skin. | DUKE |
| anti estrogenic | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti herpetic | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti histaminic | 37956 | Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. | DUKE |
| anti HIV | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti inflammatory | 35472 | A substance that reduces or suppresses inflammation. | DUKE |
| anti leukemic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti melanomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti metastatic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti mutagenic | | | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti peristaltic | | | DUKE |
| anti proliferant | | | DUKE |
| anti spasmodic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti stress | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti thyroid | | | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anxiolytic | 35474 | Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. | DUKE |
| apoptotic | | | DUKE |
| aromatase inhibitor | 50790 | An EC 1.14.14.* (oxidoreductase acting on paired donors, incorporating of 1 atom of oxygen, with reduced flavin or flavoprotein as one donor) inhibitor which interferes with the action of aromatase (EC 1.14.14.14) and so reduces production of estrogenic steroid hormones. | DUKE |
| beta-glucuronidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| calcium antagonist | 48706 | Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. | DUKE |
| cancer preventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| choleretic | | | DUKE |
| central nervous system depressant | 35470 | A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. | DUKE |
| cyclooxygenase-1 inhibitor | 50630 | A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 1. | DUKE |
| cyclooxygenase-2 inhibitor | 50629 | A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. | DUKE |
| cyclooxygenase inhibitor | 35544 | A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. | DUKE |
| cytochrome-P450-1A1 inhibitor | 50183 | An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| deiodinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| differentiator | | | DUKE |
| diuretic | 35498 | An agent that promotes the excretion of urine through its effects on kidney function. | DUKE |
| DNA-protective | | | DUKE |
| estrogenic | | | DUKE |
| HIF-1alpha inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| hyaluronidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hypotensive | | | DUKE |
| ICAM-1 inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| IKK inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| iNOS inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| inotropic | | | DUKE |
| interleukin-6 inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| monoamine-oxidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| mitogen-activated-protein-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| musculotropic | | | DUKE |
| mutagenic | | | DUKE |
| myorelaxant | | | DUKE |
| NADPH-oxidase inhibitor | 50423 | An EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor that interferes with the action of NAD(P)H oxidase (H2O2-forming), EC 1.6.3.1. | DUKE |
| NF-kappa-B inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| nitric-oxide-synthase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| nodulation signal | | | DUKE |
| ornithine-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| cytochrome-P21 inducer | | | DUKE |
| pesticide | 25944 | Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. | DUKE |
| protein kinase C inhibitor | 37700 | An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). | DUKE |
| polyamine synthesis inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| progestational | | | DUKE |
| protein-tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| quinone-reductase inducer | | | DUKE |
| radioprotective | 35232 | Any pharmaceutical compound containing a radioisotope. | DUKE |
| sedative | 35717 | A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. | DUKE |
| sunscreen | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| TNF-alpha inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| topoisomerase-II inhibitor | 50750 | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | DUKE |
| topoisomerase-I inhibitor | 50276 | A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. | DUKE |
| utero trophic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| vasodilator | 35620 | A drug used to cause dilation of the blood vessels. | DUKE |
| VEGF inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| xanthine oxidase inhibitor | 35634 | An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). | DUKE |
