Health Effect: topoisomerase-II poison
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Name | topoisomerase-II poison | ||||||
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ChEBI ID | 50750 | ||||||
ChEBI Name | topoisomerase II inhibitor | ||||||
ChEBI Definition | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | ||||||
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