| angiotensin converting enzyme inhibitor | 35457 | An EC 3.4.15.* (peptidyl-dipeptidase) inhibitor that interferes with the action of peptidyl-dipeptidase A (EC 3.4.15.1). | DUKE |
| acetyl-CoA-carboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| aldose reductase inhibitor | 48550 | An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). | DUKE |
| allergenic | 50904 | A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. | DUKE |
| anti acne | 50177 | A drug used to treat or prevent skin disorders or for the routine care of skin. | DUKE |
| anti aggregant | | | DUKE |
| anti allergic | 50857 | A drug used to treat allergic reactions. | DUKE |
| anti angiogenic | 48422 | An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. | DUKE |
| anti bacterial | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti cancer | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti cariogenic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti hepatotoxic | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| anti ischemic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti leukemic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti methicillin-resistant Staphylococcus aureus | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti mutagenic | | | DUKE |
| anti obesity | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti peroxidant | | | DUKE |
| anti proliferant | | | DUKE |
| anti prostat adenomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti radicular | | | DUKE |
| anti retinopathic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti ulcer | 49201 | One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| apoptotic | | | DUKE |
| beta-adrenergic receptor blocker | 37962 | Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. | DUKE |
| catechol O-methyltransferase inhibitor | 48406 | An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6). | DUKE |
| cyclooxygenase inhibitor | 35544 | A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| fungicide | 24127 | A substance used to destroy fungal pests. | DUKE |
| glucosyl-transferase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| GPTase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hepatoprotective | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| hypocholesterolemic | | | DUKE |
| immunostimulant | 50847 | A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. | DUKE |
| lipoxygenase inhibitor | 35856 | A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. | DUKE |
| methyl-guanidine inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| mitogen | 52290 | A chemical substance that encourages a cell to commence cell division, triggering mitosis. | DUKE |
| nephroprotective | 76595 | Any protective agent that is able to prevent damage to the kidney. | DUKE |
| protein kinase C inhibitor | 37700 | An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). | DUKE |
| protein-tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| radioprotective | 35232 | Any pharmaceutical compound containing a radioisotope. | DUKE |
| reverse transcriptase inhibitor | 59897 | An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need to reproduce. | DUKE |
| thermogenic | | | DUKE |
| urokinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| VEGF inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| xanthine oxidase inhibitor | 35634 | An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). | DUKE |
