| aldose reductase inhibitor | 48550 | An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). | DUKE |
| allergenic | 50904 | A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. | DUKE |
| analgesic | 35480 | An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. | DUKE |
| anti adenoviral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti aggregant | | | DUKE |
| anti aging | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti atherogenic | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| anti bacterial | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti cancer | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti carcinogenic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti depressant | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti edemic | | | DUKE |
| anti elastase | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| anti escherichic | | | DUKE |
| anti flu | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti gonadotropic | | | DUKE |
| anti hemolytic | 50248 | Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. | DUKE |
| anti hepatoadenomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti hepatotoxic | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| anti herpetic | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti histaminic | 37956 | Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. | DUKE |
| anti HIV | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti hypercholesterolemic | | | DUKE |
| anti hyperthyroid | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti inflammatory | 35472 | A substance that reduces or suppresses inflammation. | DUKE |
| anti legionella | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti leukemic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti leukotriene | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti melanogenic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti mutagenic | | | DUKE |
| anti nitrosaminic | | | DUKE |
| anti ophidic | | | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti peroxidant | | | DUKE |
| anti proliferant | | | DUKE |
| anti prostaglandin | 49020 | A chemical substance which inhibits the function of the endocrine glands, the biosynthesis of their secreted hormones, or the action of hormones upon their specific sites. | DUKE |
| anti radicular | | | DUKE |
| anti septic | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti spasmodic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti staphylococcic | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti stomatitic | | | DUKE |
| anti sunburn | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti thiamin | | | DUKE |
| anti thyroid | | | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| antitumor promoter | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti ulcerogenic | 49201 | One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. | DUKE |
| anti vaccinia | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anxiolytic | 35474 | Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions. | DUKE |
| calcium antagonist | 48706 | Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. | DUKE |
| cancer preventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| carcinogenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| chemopreventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| cholagogue | | | DUKE |
| choleretic | | | DUKE |
| clastogenic | | | DUKE |
| central nervous system active | 35470 | A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. | DUKE |
| collagen-sparing | | | DUKE |
| cyclooxygenase-2 inhibitor | 50629 | A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. | DUKE |
| cytoprotective | | | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| diuretic | 35498 | An agent that promotes the excretion of urine through its effects on kidney function. | DUKE |
| DNA-active | | | DUKE |
| DNA-protective | | | DUKE |
| fungicide | 24127 | A substance used to destroy fungal pests. | DUKE |
| hepatocarcinogenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| hepatoprotective | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| hepatotropic | | | DUKE |
| histamine inhibitor | 37956 | Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. | DUKE |
| immunostimulant | 50847 | A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. | DUKE |
| insectifuge | 24852 | Strictly, a substance intended to kill members of the class Insecta. In common usage, any substance used for preventing, destroying, repelling or controlling insects. | DUKE |
| leukotriene inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| lipoxygenase inhibitor | 35856 | A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. | DUKE |
| lyase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| metal chelator | 38161 | A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. | DUKE |
| ornithine-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| pesticide | 25944 | Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. | DUKE |
| prooxidant | | | DUKE |
| prostaglandigenic | | | DUKE |
| sedative | 35717 | A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety. | DUKE |
| sunscreen | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| tumorigenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| vulnerary | 73336 | A drug used in treating and healing of wounds. | DUKE |
| xanthine oxidase inhibitor | 35634 | An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). | DUKE |
