| aldose reductase inhibitor | 48550 | An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). | DUKE |
| allergenic | 50904 | A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. | DUKE |
| anti helmintic | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti anacarditic | | | DUKE |
| anti bacterial | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti cancer | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti cariogenic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti colitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti decubitic | | | DUKE |
| anti dermatotic | 50177 | A drug used to treat or prevent skin disorders or for the routine care of skin. | DUKE |
| anti diarrheic | 55323 | Any drug found useful in the symptomatic treatment of diarrhoea. | DUKE |
| antidote | 50247 | Any protective agent counteracting or neutralizing the action of poisons. | DUKE |
| anti dysenteric | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti encephalitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti enteritic | | | DUKE |
| anti feedant | | | DUKE |
| anti gargantitic | | | DUKE |
| anti gingivitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti hemorrhoidal | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti hepatotoxic | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| anti herpetic | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti HIV | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti hypertensive | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti lipolytic | | | DUKE |
| anti mutagenic | | | DUKE |
| anti nephritic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti nitrosaminic | | | DUKE |
| anti obesity | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti ophidic | | | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti pharyngitic | | | DUKE |
| anti polio | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti radicular | | | DUKE |
| anti renitic | | | DUKE |
| anti rhinitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti septic | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti stomatitic | | | DUKE |
| anti tonsilitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| antitumor promoter | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti ulcer | 49201 | One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| astringent | 74783 | A compound that causes the contraction of body tissues, typically used to reduce bleeding from minor abrasions. | DUKE |
| beta-adrenergic receptor blocker | 37962 | Any agent that acts on an adrenergic receptor or affects the life cycle of an adrenergic transmitter. | DUKE |
| cancer preventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| carcinogenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| cardiotoxic | 50912 | A role played by a chemical compound exihibiting itself through the ability to induce damage to the heart and cardiomyocytes. | DUKE |
| chelator | 38161 | A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. | DUKE |
| cyclooxygenase inhibitor | 35544 | A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| detoxicant | 50247 | Any protective agent counteracting or neutralizing the action of poisons. | DUKE |
| emetic | | | DUKE |
| flavor | 48318 | A substance, extract, or preparation for diffusing or imparting an agreeable or attractive smell. | DUKE |
| glucosyl-transferase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hemostat | | | DUKE |
| hepatoprotective | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| hepatotoxic | 50908 | A role played by a chemical compound exihibiting itself through the ability to induce damage to the liver in animals. | DUKE |
| immunostimulant | 50847 | A substance that augments, stimulates, activates, potentiates, or modulates the immune response at either the cellular or humoral level. A classical agent (Freund's adjuvant, BCG, Corynebacterium parvum, et al.) contains bacterial antigens. It could also be endogenous (e.g., histamine, interferon, transfer factor, tuftsin, interleukin-1). Its mode of action is either non-specific, resulting in increased immune responsiveness to a wide variety of antigens, or antigen-specific, i.e., affecting a restricted type of immune response to a narrow group of antigens. The therapeutic efficacy is related to its antigen-specific immunoadjuvanticity. | DUKE |
| immunosuppressant | 35705 | An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response. | DUKE |
| lipoxygenase inhibitor | 35856 | A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. | DUKE |
| monoamine-oxidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| ornithine-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| pesticide | 25944 | Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. | DUKE |
| psychotropic | 35471 | A loosely defined grouping of drugs that have effects on psychological function. | DUKE |
| reverse transcriptase inhibitor | 59897 | An EC 2.7.7.* (nucleotidyltransferase) inhibitor that interferes with the activity of reverse transcriptase, EC 2.7.7.49, a viral DNA polymerase enzyme that retroviruses need to reproduce. | DUKE |
| topoisomerase-II inhibitor | 50750 | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | DUKE |
| xanthine oxidase inhibitor | 35634 | An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). | DUKE |
