| 11beta-hydroxysteroid-dehydrogenase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| 5-lipoxygenase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| aldehyde-oxidase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| aldose reductase inhibitor | 48550 | An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD(+) or NADP(+) acceptor) inhibitor that interferes with the action of aldehyde reductase (EC 1.1.1.21). | DUKE |
| allelochemic | | | DUKE |
| allergenic | 50904 | A chemical compound which causes the onset of an allergic reaction by interacting with any of the molecular pathways involved in an allergy. | DUKE |
| analgesic | 35480 | An agent capable of relieving pain without the loss of consciousness or without producing anaesthesia. In addition, analgesic is a role played by a compound which is exhibited by a capability to cause a reduction of pain symptoms. | DUKE |
| anti aflatoxin | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti aggregant | | | DUKE |
| anti aging | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti allergic | 50857 | A drug used to treat allergic reactions. | DUKE |
| anti Alzheimeran | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti anaphylactic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti angiogenic | 48422 | An agent and endogenous substances that antagonize or inhibit the development of new blood vessels. | DUKE |
| anti arthritic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti asthmatic | 49167 | A drug used to treat asthma. | DUKE |
| anti atherosclerotic | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| anti bacterial | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti carcinomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti cariogenic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti cataract | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti colitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti complementary | | | DUKE |
| anti Crohn's | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti cystitic | | | DUKE |
| anti depressant | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti dermatitic | 50177 | A drug used to treat or prevent skin disorders or for the routine care of skin. | DUKE |
| anti diabetic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti elastase | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| anti encephalitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti escherichic | | | DUKE |
| anti estrogenic | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti feedant | | | DUKE |
| anti fibrosarcomic | | | DUKE |
| anti flu | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti gastric | | | DUKE |
| anti gonadotropic | | | DUKE |
| anti glucose-tolerance-factor | | | DUKE |
| anti hepatotoxic | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| anti herpetic | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti histaminic | 37956 | Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. | DUKE |
| anti HIV | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti hydrophobic | | | DUKE |
| anti hypertensive | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti inflammatory | 35472 | A substance that reduces or suppresses inflammation. | DUKE |
| anti leishmanic | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti leukemic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti leukotriene | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| anti lipoperoxidant | | | DUKE |
| anti malarial | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti melanomic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti metastatic | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti mutagenic | | | DUKE |
| anti myocarditic | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| anti nitrosaminic | | | DUKE |
| anti nociceptive | 35470 | A class of drugs producing both physiological and psychological effects through a variety of mechanisms involving the central nervous system. | DUKE |
| antioxidant | 22586 | A substance that opposes oxidation or inhibits reactions brought about by dioxygen or peroxides. In European countries, E-numbers for permitted antioxidant food additives are from E 300 to E 324. | DUKE |
| anti pancreatitic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti periodontal | | | DUKE |
| anti peristaltic | | | DUKE |
| anti permeability | | | DUKE |
| anti peroxidant | | | DUKE |
| anti pharyngitic | | | DUKE |
| anti plaque | | | DUKE |
| anti plasmodial | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| anti premenstrual syndrome | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti podriac | | | DUKE |
| anti polio | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| anti proliferant | | | DUKE |
| anti prostanoid | | | DUKE |
| anti prostatitic | | | DUKE |
| anti psoriac | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti radicular | | | DUKE |
| anti spasmodic | 52217 | Any substance introduced into a living organism with therapeutic or diagnostic purpose. | DUKE |
| anti streptococcic | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| anti thiamin | | | DUKE |
| anti thrombic | 50248 | Drug that acts on blood and blood-forming organs and those that affect the hemostatic system. | DUKE |
| anti trypanosomic | 33281 | A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans. | DUKE |
| antitumor | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| antitumor promoter | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| anti ulcer | 49201 | One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract. | DUKE |
| anti viral | 22587 | A substance that destroys or inhibits replication of viruses. | DUKE |
| apoptotic | | | DUKE |
| ATPase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| bacteristat | 33282 | A substance that kills or slows the growth of bacteria. | DUKE |
| bradycardiac | 38070 | A drug used for the treatment or prevention of cardiac arrhythmias. Anti-arrhythmia drugs may affect the polarisation-repolarisation phase of the action potential, its excitability or refractoriness, or impulse conduction or membrane responsiveness within cardiac fibres. | DUKE |
| calmodulin antagonist | 48706 | Substance that attaches to and blocks cell receptors that normally bind naturally occurring substances. | DUKE |
| cAMP-phosphodiesterase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| cancer preventive | 35610 | A substance that inhibits or prevents the proliferation of neoplasms. | DUKE |
| candidicide | | | DUKE |
| capillariprotective | | | DUKE |
| carcinogenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| catabolic | | | DUKE |
| catechol O-methyltransferase inhibitor | 48406 | An EC 2.1.1.* (methyltransferase) inhibitor that interferes with the action of catechol O-methyltransferase (EC 2.1.1.6). | DUKE |
| copper chelator | 38161 | A ligand with two or more separate binding sites that can bind to a single metallic central atom, forming a chelate. | DUKE |
| cyclooxygenase-2 inhibitor | 50629 | A cyclooxygenase inhibitor that interferes with the action of cyclooxygenase 2. | DUKE |
| cyclooxygenase inhibitor | 35544 | A compound or agent that combines with cyclooxygenases (EC 1.14.99.1) and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of icosanoids, prostaglandins, and thromboxanes. | DUKE |
| cytochrome-P450-1A2 inhibitor | 50183 | An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. | DUKE |
| cytochrome-p450 inducer | | | DUKE |
| cytochrome-P450 inhibitor | 50183 | An enzyme inhibitor that interferes with the activity of cytochrome P450 involved in catalysis of organic substances. | DUKE |
| cytotoxic | 52209 | A role played by the molecular entity or part thereof which causes the development of a pathological process. | DUKE |
| deiodinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| diaphoretic | | | DUKE |
| differentiator | | | DUKE |
| estrogenic | | | DUKE |
| fungicide | 24127 | A substance used to destroy fungal pests. | DUKE |
| glucosyl-transferase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hemostat | | | DUKE |
| hepatomagenic | | | DUKE |
| hepatoprotective | 62868 | Any compound that is able to prevent damage to the liver. | DUKE |
| HIV-reverse-transcriptase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| hypoglycemic | 35526 | A drug which lowers the blood glucose level. | DUKE |
| iNOS inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| inotropic | | | DUKE |
| insulinogenic | | | DUKE |
| juvabional | | | DUKE |
| larvistat | | | DUKE |
| lipoxygenase inhibitor | 35856 | A compound or agent that combines with lipoxygenase and thereby prevents its substrate-enzyme combination with arachidonic acid and the formation of the icosanoid products hydroxyicosatetraenoic acid and various leukotrienes. | DUKE |
| monoamine-oxidase-A inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| mast-cell stabilizer | | | DUKE |
| metalloproteinase inhibitor | 50664 | | DUKE |
| matrix-metalloproteinase-9 inhibitor | 50664 | | DUKE |
| mutagenic | | | DUKE |
| NADPH-oxidase inhibitor | 50423 | An EC 1.6.3.* (oxidoreductase acting on NADH or NADPH with oxygen as acceptor) inhibitor that interferes with the action of NAD(P)H oxidase (H2O2-forming), EC 1.6.3.1. | DUKE |
| neutral-endopeptidase inhibitor | 59107 | Any EC 3.4.* (hydrolases acting on peptide bond) inhibitor that interferes with the activity of a metalloendopeptidase (EC 3.4.24.*). | DUKE |
| neuroprotective | 63726 | Any compound that can be used for the treatment of neurodegenerative disorders. | DUKE |
| NF-kappa-B inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| nitric-oxide inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| nitric-oxide-synthase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| ornithine-decarboxylase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| pesticide | 25944 | Strictly, a substance intended to kill pests. In common usage, any substance used for controlling, preventing, or destroying animal, microbiological or plant pests. | DUKE |
| prostaglandin-E2 inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| phospholipase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| protein kinase C inhibitor | 37700 | An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13). | DUKE |
| plasmodicide | | | DUKE |
| proliferant | | | DUKE |
| prostaglandin synthesis inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| protein-tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| quinone-reductase inducer | | | DUKE |
| teratologic | | | DUKE |
| TNF-alpha inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| topoisomerase-II inhibitor | 50750 | A topoisomerase inhibitor that inhibits DNA topoisomerase (ATP-hydrolysing), EC 5.99.1.3 (topoisomerase II), which catalyses ATP-dependent breakage of both strands of DNA, passage of the unbroken strands through the breaks, and rejoining of the broken strands. | DUKE |
| topoisomerase-I inhibitor | 50276 | A topoisomerase inhibitor that inhibits the bacterial enzymes of the DNA topoisomerases, Type I class (EC 5.99.1.2) that catalyze ATP-independent breakage of one of the two strands of DNA, passage of the unbroken strand through the break, and rejoining of the broken strand. These bacterial enzymes reduce the topological stress in the DNA structure by relaxing negatively, but not positively, supercoiled DNA. | DUKE |
| tumorigenic | 50903 | A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities. | DUKE |
| tyrosinase inhibitor | 59997 | Any EC 1.14.18.* (oxidoreductase acting on paired donors, miscellaneous compound as one donor, incorporating 1 atom of oxygen) inhibitor that interferes with the action of tyrosinase (monophenol monooxygenase), EC 1.14.18.1, an enzyme that catalyses the oxidation of phenols (such as tyrosine) and is widespread in plants and animals. | DUKE |
| tyrosine-kinase inhibitor | 23924 | A compound or agent that combines with an enzyme in such a manner as to prevent the normal substrate-enzyme combination and the catalytic reaction. | DUKE |
| vasodilator | 35620 | A drug used to cause dilation of the blood vessels. | DUKE |
| VEGF inhibitor | 35222 | A substance that diminishes the rate of a chemical reaction. | DUKE |
| xanthine oxidase inhibitor | 35634 | An EC 1.17.3.* (oxidoreductase acting on CH or CH2 with oxygen as acceptor) inhibitor that interferes with the action of xanthine oxidase (EC 1.17.3.2). | DUKE |
| protein kinase inhibitor | 37699 | An EC 2.7.* (P-containing group transferase) inhibitor that interferes with the action of protein kinases. | CHEBI |
